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View Dons full profile See who you know in common Get introduced Contact Don directly Other similar profiles Matthew Joynt Matthew Joynt Mequon-Thiensville School District 3K followersMilwaukee, WI Robert R

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The ZDHHC21T209S/T209S mouse model confirms that the mutation significantly increases neuronal excitotoxicity susceptibility and triggers synaptic dysfunction by enhancing FYN palmitoylation, leading to NMDAR2B overactivation and dysfunction and neuronal loss, ultimately resulting in cognitive deficits (168)