chac1 er stress glutathione degradation (GSH) depletion by results in a more oxidizing Glutathione-specific gamma–glutamylcyclotransferase 1 (CHAC1) increases
Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine A scheme of the mechanism of CHAC1 degradation of glutathione enhancing Download Scientific Diagram The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2: Cell Reports Dysregulated lipids homeostasis disrupts CHAC1 mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer ScienceDirect
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