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A caveat of all guidelines is that when a positive finding is seen, the diagnosis is highly accurate (specificity 97% and 95% with TVUS and MRI, respectively), but if endometriosis is not detected, then sensitivity is only moderate (63% and 73%, respectively), 12 and endometriosis cannot be excluded

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Use of metformin to treat pregnant women with polycystic ovary syndrome (pregmet2): a randomised, double-blind, placebo-controlled trial

These patients present with systemic sclerosis-like lesions, mild-to-moderate proximal muscle weakness, arthritis in the form of subluxation of the interphalangeal joints, mechanics hands, Raynaud phenomenon, and interstitial lung disease