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[72] When activated, PPIs bind covalently to cysteine residues on the H + /K + ATPase on the luminal side of the parietal cell membrane and thus inhibit acid secretion

J Alzheimers Dis (2018) 63:133746

In castrated monkeys at equivalent doses, a single administration lowered serum LH levels more significantly and with a longer duration compared with elagolix