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Shortness of breath, rapid breathing, coughing (sometimes with bloody sputum), fever, and sudden worsening of symptoms are red flags for pulmonary causes

doi: 10.3390/cells8101280 111 Ragerdi KashaniIHedayatpourAPasbakhshPKafamiLAtlasiNPirhajati MahabadiVet al

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However, this broader action means a higher chance of gastrointestinal side effects early on