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The modest weight loss observed after switching to DOR is clinically meaningful given that most individuals included were overweight or obese at switch to DOR and that weight gain has often been associated with female sex, especially during perimenopause and menopause

Once an aligned peak list was created, features ( m/z and retention time pairs) present in the first blank sample of the run were deleted as a means of blank filtering

This is even more important since FMN and FAD are integral components of the electron transport chain (ETC), a vital part of cellular respiration