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Despite their effectiveness, the long-term use of TCS is limited by a number of well-documented drawbacks

PLoS ONE 8 , e62617 (2013)

Research has demonstrated that baicalein suppresses the NF-B signaling pathway in MPTP-induced PD mice models, which lowers the production of pro-inflammatory cytokines and, in turn, decreases astrocyte activation (Lee et al., 2014)