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Nutritional risk factors, microbiota and Parkinsons disease: what is the current evidence

Side effects are uncommon and typically mild

Analysis of the large VITATOPS study, which was a cohort of 1,400 participants expanding over 10 countries, found a significant reduction (~4 mol/L) in homocysteine in the group receiving vitamin B12, folate, and vitamin B6 supplementation compared to the control (29, 30)