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Cases involving the use of the RNS System are identified by the reporting of an ICD-10-PCS code combination capturing a neurostimulator generator inserted into the skull with the insertion of a ( neurostimulator lead into the brain and the cases are assigned to MS-DRG 023 (Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis with MCC or Chemotherapy Implant or Epilepsy with Neurostimulator) when reported with a principal diagnosis of epilepsy

Percent change (the primary outcome) within and between treatment arms were estimated by modelling the log of the ratio of the month 6 and baseline plaque measures and then exponentiating the relevant model parameter estimates, subtracting one, and multiplying by 100

Combined Iron Chelator with N-Acetylcysteine Exerts the Greatest Effect on Improving Cardiac Calcium Homeostasis in Iron-Overloaded Thalassemic Mice