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Description

In our assay, 2.5 M strep-MBP-ROXY9 deglutathionylated 0.018 M GAPDH in 20 min

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Our CTC-based correlative studies demonstrate that effective therapeutic responses to the ARPI/BCL-2i combination in mCRPC patients may require concurrent suppression of AR and BCL-2 and clearance of CTCs whereas treatment resistance is marked by persistent CTC burden and associated with activation of alternative survival pathways such as GR

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Antioxidants capacity can be estimated by considering the final effects of their presence, by the use of in vitro tests, or directly by more complex methods utilizing exogenic probes to detect oxidation

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PMID: 27770074, PMCID: PMC5123555, DOI: 10.1212/wnl.0000000000003353

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