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Experimental studies have shown that metformin treatment can improve cognitive performance in female mice with APP transgenic models (180)

The researchers examined the impact of these interventions through a biochemical characterization of brain homogenates, quantifying oxidative and inflammatory markers such as lipid peroxides, glutathione (GSH), glutathione S-transferase (GST), 5-lipoxygenase (5-LOX), cyclooxygenase-2 (COX-2), leukotriene B4, prostaglandin E2, and ascorbic acid using spectrophotometric assays and ELISA

Table 1 Summary of DVT treatment strategies targeting NETs

These layer-by-layer Se nanocomplexes (LBL Se-NCs) were characterized in terms of their size, surface charge, stability, siRNA-binding capacity, and siRNA release profile