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This suggests that lifestyle modifications may be necessary as an effective treatment for pillar pain, particularly for patients who are reporting higher pain levels even after all therapeutic options are exhausted

Overall, this phase 1b trial demonstrates that combined cagrilintide and semaglutide therapy is safe, well-tolerated, and offers clinically meaningful weight loss compared to placebo, warranting further investigation for weight management in obesity

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The most common side effect is mild injection site irritation