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Cell 186(22):47374756 Sadler AJ, Williams BRG (2007) Structure and function of the protein kinase R

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This work is also supported by the BLR&D/DMRS Award (1I01BX005051) to A.V.S

Furthermore, the histone lysine methyltransferase SETD1A contributes to sorafenib resistance, suggesting that targeting SETD1A could improve therapeutic outcomes in HCC [111]