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Therefore, targeted small molecule inhibitors of the NNMT could be significantly beneficial as molecular probes for mechanistic investigations and for the development of therapeutics for the treatment of metabolic and chronic disease conditions that are characterized by abnormal NNMT activity

PubMed Randomized trialRetatrutide evidence2023 Triple-Hormone-Receptor Agonist Retatrutide for Obesity, A Phase 2 Trial Primary human trial source for retatrutide obesity efficacy and safety discussions