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3 Department of Anesthesia and Critical Care, Holy Family Hospital, Steward Health Care, Methuen, MA, USA Correspondence: Zhongcheng Shi Tel +1- 832-824-0814 Email [email protected] Abstract: The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known for inducing multisystem organ dysfunction associated with significant morbidity and mortality

The semi-synthetic derivative and major active metabolite of artemisinin, dihydroartemisinin (DHA), has been shown to increase ferroptosis in lung cancer cells by inactivating the PRIM2/SLC7A11 axis, 285 as well as in head and neck cancers 286 and glioblastoma cell lines 287 by inhibiting GPX4

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