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[174] He reached the Super Bowl for the first time in his career, scoring a touchdown and a two-point conversion in the 4022 loss to the Philadelphia Eagles

Its core pathophysiological characteristics are intricately intertwined with abnormal iron and lipid metabolism, oxidative stress, mitochondrial dysfunction, and neuroinflammation, driving the progressive degeneration of dopaminergic neurons in the substantia nigra (SN) ( Figure 2 )