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In contrast, IL-10 was downregulated and decreased significantly in the BacA group at 16 weeks post inoculation, and the expression of IL-10 was significantly lower than uninfected control ( Figure 7C )

(2.1, 2.2) Initiate folic acid 400 mcg to 1000 mcg orally, once daily, beginning 7 days prior to the first dose of pemetrexed for injection and continue until 21 days after the last dose of pemetrexed for injection

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