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The role of autophagy and mitophagy in NDDs Autophagy and mitophagy are indispensable for neuronal survival, given the post-mitotic nature of neurons, their extraordinary metabolic demands, and their reliance on precise proteostasis and mitochondrial quality control

We found that supplementation with L-GSH for three months was able to reduce the levels of MDA in all blood components, including plasma ( Figure 4C ), PBMCs ( Figure 4D ), and RBCs ( Figure 4E )

Article contents Glycine supplementation can partially restore oxidative stress-associated glutathione deficiency in ageing cats Published online by Cambridge University Press: 29 February 2024 Abstract Intracellular levels of glutathione, the major mammalian antioxidant, are reported to decline with age in several species