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Gap junction dysfunction in the prefrontal cortex induces depressive-like behaviors in rats

Statistical analysis The statistical significance of the difference between two groups was analyzed using an unpaired two-tailed Students t test

Significant differences compared to MCF7-GSTP1 membranes are indicated with **** p 0.0001, (one-way ANOVA with Dunnett multiple comparisons test)

Instead, the combined data are more consistent with the premise that p53, by virtue of regulating genes that contribute to ferroptosis, regulates the sensitivity of cells to this pathway, rather than directly induces ferroptosis