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Consistent with this evidence, the results of the present study revealed that EVs isolated from the serum of OW/Ob patients with BC increased the oxidative phosphorylation and the ATP production in BC cells compared with those treated with EVs isolated from NW patients

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On the other hand, serum measurement of zonulins, an integral part of the intercellular TJs, detects barrier disassembly and increased permeability [33]