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The physiopathology reviewed in this article focused on the lipotoxicity associated with metabolic syndrome and considers NAFLD as a final expression of this abnormality that can have significant liver morbidity and mortality

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ERFFI1 (ErbB receptor feedback inhibitor 1) is constitutively expressed and there is excess mitogenic signaling

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Neuron 13:713725 Chen Y, Swanson RA (2003) The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures

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If this balance is disrupted, it can lead to copper overload and zinc deficiency

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