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Aggregation/cloudiness: dilute sample, change buffer ionic strength, reduce peptide concentration, or filter (if compatible) through low-protein-binding filters

These plans should consider each patients unique needs and risks based on their treatment

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Conclusions In summary, our study evidenced that AT-specific B12 deficiency significantly dysregulated AT lipid metabolism and inflammation, thereby promoting dyslipidemia and worsening obesity-related complications that could underlie the development of IR and cardiometabolic risk