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These results indicate that combinations of pulmonary therapeutics with atropine or drugs that inhibit mucous secretion are important for the treatment of respiratory toxicity and lung injury following VX exposure

Notably, epithelial-mesenchymal transition (EMT) activity was enriched in both the M1 cluster and post-treatment metastases, while MYC activity was more prominent in pretreatment metastases and the M2 cluster, suggesting that these metastatic phenotypes may be influenced by treatment exposure