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doi: 10.3389/fphys.2022.820398 277 SilvermanMNSternbergEM

Additionally, lfpA is required for optimal virulence in animal models, as deletion of IfpA results in a 4.5-fold-decrease in LD 50 and a delayed time-to-death in Syrian hamsters and BALB/c mice [Citation177]

A Phase 1b study first established that co-administering cagrilintide with semaglutide 2.4 mg was tolerable and characterized cagrilintides pharmacokinetics, including its multi-day half-life of roughly 159195 hours