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However, this increased phosphorylation of AKT is not due to PTPN22 phosphatase activity, as pharmacological inactivation of PTPN22 activity by treating cells with the PTPN22 inhibitor (PTPN22-IN-1) does not affect AKT phosphorylation

Tumor thickness and mitotic rate robustly predict melanoma-specific survival in patients with primary vulvar melanoma: A retrospective review of 100 cases