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The metabolically active forms of vitamin B12 are methylcobalamin and 5-deoxy adenosylcobalamin

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The parenteral administration also halts the progression of neurological damage associated with B12 deficiency, but the complete improvement of the condition may depend on the severity and extent of the deficiency.[12][13] Contraindications & Precautions Cyanocobalamin is contraindicated in those with hypersensitivity to cobalt moiety or cobalamin molecule due to the risk of anaphylaxis.[21] Warnings: The use of cyanocobalamin is warned in patients with early Lebers disease as there have been reports of severe and swift optic atrophy with its administration

Mountainside Medical recommends that all clinical use decisions be made in accordance with the relevant drug prescribing information, institutional protocols, and applicable USP standards