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4, the vasodilator producing endothelial nitric oxide (NO) synthase (eNOS) is decreased, while the vasoconstrictor endothelin-1 is increased

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Several studies in humans have also confirmed the effects of aging on the intestinal immune response

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It has been proposed that the function of SLIM1 may be regulated by condition-dependent proteinprotein interactions (PPIs) and/or post-translational modifications (Wawrzyska and Sirko, 2014)

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