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B 109 (43), 2020720214 (2005)

These properties influence the way they interact with surrounding amino acids in polypeptides and proteins, and consequently impact protein 3D structure and properties

2013) but are the most reactive and therefore dangerous molecules, especially OH

Although the use of primary brain endothelial cells and/or co-culture with other cells would provide a physiologically more relevant environment, bEND.3 cells consistently show a stable barrier function and thus have been widely used in previous studies on BBB permeability to therapeutics 35