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Among often used dietary animal models belong HFD, modified HFD (addition of carbohydrates, cholesterol, trans-fats or CCl 4 ), methionine- and choline-deficient diet, and choline-deficient L-amino-defined diet

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It is absorbed in the small intestine, and a daily intake of 600 IU (15 g) is recommended for both men and women (800 IU (20 g) for those over 70 years of age) ( Figure 1 Vitamin D deficiency can result from inadequate intake or absorption, or from hepatic and/or renal insufficiency, which impairs the conversion of the vitamin to its active form

doi:10.1136/bmjopen-2023-077986