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HS: Validation, Visualization, Writing review & editing

We hypothesized that LV morphological and functional abnormalities identified by CMR are part of the phenotypic expression of MVP even with preserved LV ejection fraction (LVEF) and in the absence of significant MR

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To date, yeast Saccharomyces cerevisiae and Drosophila are the two organisms whose lipidomics has been studied at whole organism level, with tremendous advance in quantification of some of the SL classes (such as ceramide, hexosylceramide and phosphoethanolamine ceramide for fly), as well as in identification of the connections between cell behavior and SL alteration [12, 20-22]