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Chronic Constipation and Diarrhea Slowed-down peristalsis due to the nicotine effect on smooth muscle cells found within walls of the intestines may lead to prolonged transit time, hence chronic constipation while increased activity can cause rapid passing of food leading to watery stools thus diarrhea

Analysts at Jefferies said the scant progress update on NJOY, combined with the slowdown in traction of its nicotine pouch product on!, meant the market may not view this as a good quarter for Altria