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Treatment consists of replacement of kidney tubular losses, symptomatic management of systemic complications, and specific therapy directed at the basic defect, i.e., lysosomal cystine accumulation

This duality underscores the critical importance of microbial community composition over total amino acid load: a eubiotic microbiome channels tryptophan and methionine toward protective metabolites, whereas dysbiosis skews production toward nephrotoxins

Iron also acts as a common prosthetic group composed of protoporphyrin IX and a Fe 2+ ion

Developments such as these spurred interest in the reactions by which oxidizing ROS could be prevented from accumulating to detrimental levels in the illuminated chloroplast