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Within this integrated model, UA-driven mitophagy initiation, ALA-supported flux completion, and EGT-mediated mitochondrial stabilization converge to modulate the ferroptosismitophagy regulatory axis in cardiometabolic pathology through complementary mechanisms

Creatine helps rapidly regenerate ATP through the phosphocreatine system

For functional profiling, bwa-mem was used with the default setting to align the preprocessed reads against the integrated gene catalog (IGC), a comprehensive database comprising 9,879,896 genes specific to the human gut microbiome functionality [41, 42]

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