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Finally, 2 l 30% glycerol (in reservoir solution) was added to the drop before picking the crystal using 0.1 mm litholoops and flash-freezing it in liquid nitrogen

Redox-controlled reversible modifications regulate UPR signaling, for example, thiol oxidation of ER molecular chaperones such as the binding immunoglobulin protein/78-kDa glucose-regulated protein (BiP/Grp78) that enhances the release of BiP from ER stress sensors and activates UPR (Wang et al., 2014)

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