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Thus, the scientific community has concluded that the mislocalization of TDP43 in the cytosol happens and cleavage, phosphorylation, and ubiquitination are some of the exciting features illuminated in sporadic ALS and frontotemporal dementia (Brown and Al-Chalabi, 2017)

Similarly, sleep deprivation can impair the balance between the appetitesuppressing hormone leptin and the hungerstimulating hormone ghrelin, causing the brain to receive a false energy deficit signal, thereby intensifying hunger and cravings and ultimately leading to weight gain [38]

F.) 10251037 (Academic, New York, 1975)

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