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Phase 2 Obesity Trial Jastreboff et al., New England Journal of Medicine (2023) Jastreboff and colleagues conducted a phase 2, double-blind, randomized, placebo-controlled trial of retatrutide in adults with obesity

Cystoscopy - In this test, the doctor inserts a flexible telescope into the urethra and passes it into the bladder to inspect the bladder lining for tumors or other problems

This method allows self-administration of NAD at home (after medical guidance) and provides high bioavailability without the need for an IV line

Baseline labs: IGF-1, fasting glucose, HbA1c, lipid panel, and comprehensive metabolic panel are standard before initiation