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scRNA-seq analysis revealed high expression of advanced differentiation-stage markers, including those of secreted products ( PAEP , DEFB1 ), glands ( SCGB2A2 ) and ciliated cells ( FOXJ1 , PIFO ) (Fig

Supporting this finding, there are reports that show that among B vitamins, vitamin B1 plays an important role in appetite control and its deficiency is associated with loss of appetite and body weight.[6] Based on macroscopic and microscopic parameters, all treatment groups with selected B vitamins, except the mega dose of vitamin B6, were effective to reduce the evaluated colitis parameters in a significant manner

doi: 10.3389/fnins.2026.1814098 Received 19 February 2026 Revised 03 April 2026 Accepted 03 April 2026 Published 22 April 2026 Volume 20 - 2026 Edited by Balaji Govindaswami, Independent Researcher, San Pedro, United States Reviewed by Mohsen Khosravi, Zahedan University of Medical Sciences, Iran Laishuan Wang, Fudan University, China Updates Copyright 2026 Kang, Shao, Shi, Wang, Xiong, Jin and Ren

doi: 10.1089/thy.2022.0505 5 WeetmanAP