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In some cases, gallstones cause chronic inflammation in the gallbladder ( chronic cholecystitis ), leading to thickening of the gallbladder walls (Jones, Ferguson 2018)

Diagnostic Findings Laryngeal signs: LPR commonly shows hyperemia, edema, and thickened mucus of the posterior larynx, along with pseudosulcus or vocal fold granuloma detectable on flexible or rigid laryngoscopy

Taken together, these findings provide strong evidence that mitophagy deficits specifically in microglia can contribute to PD-like degeneration, and this is likely driven by inflammasome-mediated immune activation

miR-126 regulates angiogenic signaling and vascular integrity