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Compounds were initially tested for NNMT inhibition activity at 100 M or 1 mM concentration (compounds with no activity at 100 uM were tested at 1 mM concentration)

However, researchers and clinicians have observed its potential in a much broader population, especially in the context of: Visceral adiposity (deep belly fat) Growth hormone deficiency Cognitive aging Cardiometabolic risk reduction Its appeal lies in the ability to elevate IGF-1 (insulin-like growth factor-1) levels while preserving the bodys natural feedback mechanisms

"The Controversial Role of Homocysteine in Neurology: From Labs to Clinical Practice"

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