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Taghizadeh N, Mohammadi S, Yousefi Z, Golpour P, Taheri A, Maleki MH, Nourbakhsh M, Nourbakhsh M, Azar MR

part of MDHA is reduced to AsA under the catalyzation of MDHAR, and the other part is oxidized to DHA

In mammalian cells NAD + is synthesized by three main pathways: (i) de novo biosynthesis pathway, through the Kynurenine pathway, where tryptophan as the precursor, is catabolized to quinolinic acid, to generate NAD +