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B12 is one important piece, but persistent exhaustion usually has more than one contributing factor

The amount of water changes the concentration, which changes how many units you draw for each dose

You can find the signs of a weak immune system here

Instead: Talk to your GP or specialist about your symptoms Ask for support to manage skin side effects if they occur Take a holistic approach to skin health think about your gut health, blood glucose, nutrient levels and skin microbiome alongside treatment As discussed in the case studies, if B12 injections caused a flare, it seemed to either settle on its own after a few weeks, or topical treatments were used to support the skin afterwards