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Furthermore, the inhibition of p38 MAPK also abolished the radiation-induced expressions of EMT marker proteins, indicating that H 2 S/CSE promoted long-term metastasis of HCC cells after irradiation through promoting EMT by activating the p38 MAPK pathway, therefore inducing the invasion and metastasis of HCC cells and the xenograft tumors (Zhang et al., 2018)

Once isolated and purified, the exosomes are injected intravenously or applied topically or locally, depending on the treatment goal

Nasal spray delivery Nasal spray delivery offers an alternative route that avoids both the skin barrier and digestive degradation

A case of conjunctival bee sting injury with review of the literature on ocular bee stings