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Nicotinamide was highly correlated with serum insulin, HOMA-IR, final body weight, total adipose mass, liver triglyceride, and serum glucose (r = 0.50 to 0.73), while N-acetylserotonin was negatively correlated with all phenotypic parameters except liver malondialdehyde (r = 0.50 to 0.72)

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Subsequent surface plasmon resonance (SPR) analysis showed binding affinity ( K D ) 674.3 nM for prothrombin, 8.48 M for collagen, 160 nM for fibrinogen (Supplementary Fig

DOI: 10.1113/jphysiol.1934.sp003147 Gericke A et al (2011): Role of M1, M3, and M5 muscarinic acetylcholine receptors in cholinergic dilation of small arteries studied with gene-targeted mice