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This selective binding initiates both genomic and non-genomic estrogenic responses that disrupt normal hormonal balance ( 3.1.2 Membrane receptor and calcium signaling dysregulation 3.1.2.1 Calcium homeostasis disruption EED exposure significantly disrupts intracellular calcium homeostasis, leading to aberrant Ca 2+ signaling patterns that compromise sperm function

doi: 10.3389/fnmol.2023.1242925 254 NedergaardM

Elevated histone Kla enhances the expression of neuronal activity markers such as c-Fos, leading to reduced social behavior and increased anxiety

Key Players: China Biologic Products Holdings Inc., Teva Pharmaceuticals, Wellona Pharma, Merck, AdvaCare Pharma