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Furthermore, hydrogen bonds are observed among residues D212, L221, and H253 of mVP35d and residues K328, Q360, and S324 of MARL, respectively, further facilitating the attachment of mVP35d IID to MARL (Fig

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In a randomized, double-blind, placebo-controlled trial in 2,919 participants (65 years) with elevated blood concentrations of homocysteine, supplementation with vitamin B 12 (500 g/day) and folic acid (400 g/day) for two years did not decrease the risk of osteoporotic fracture despite reductions in homocysteine (120, 121)