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Description

Colorectal cancer metastatic dMMR immuno-therapy (COMMIT) study: A randomized phase III study of atezolizumab (atezo) monotherapy versus mFOLFOX6/bevacizumab/atezo in the first-line treatment of patients (pts) with deficient DNA mismatch repair (dMMR) or microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC)NRG-GI004/SWOG-S1610

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[DOI] [PubMed] [Google Scholar] 168.Filipek PA, Juranek J, Nguyen MT, Cummings C, Gargus JJ

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Despite sharing identical genetic backgrounds, monozygotic twins often display significant phenotypic differences in schizophrenia and other complex disorders, suggesting that factors beyond genetic variation contribute to disease risk

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