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When skin is injured, IGF-1 stimulates the proliferation of keratinocytes, the primary cells in the epidermis, and fibroblasts, the cells responsible for producing collagen and other extracellular matrix components

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of the preamble of this proposed rule to use FY 2022 data in the FY 2024 LTCH PPS ratesetting, we obtained total charges from FY 2022 Medicare LTCH claims data from the December 2022 update of the FY 2022 MedPAR file and used proposed Version 41 of the GROUPER to classify LTCH cases