parkinson glutathione oxidative ipsc crispr S-transferase: A keystone in Parkinson's disease pathogenesis and therapy In Vitro CRISPR/Cas9-Directed Gene Editing
In Vitro CRISPR Cas9 Directed Gene Editing to Model LRRK2 G2019S Parkinson's Disease in Common Marmosets Scientific Reports Ferroptosis is a type of cell death driven by uncontrolled peroxidation of membrane phospholipids. Glutathione peroxidase 4 (GPX4) is the main regulator of ferroptosis, but how it protects membranes is not well Human pluripotent stem cell engineering with CRISPRCas9 for Parkinson's disease Experimental & Molecular Medicine Genome wide CRISPRi a screens in human neurons link lysosomal failure to ferroptosis bioRxiv
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