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As expected, GCN2 was phosphorylated by either erastin or cystine starvation but not Tg, likely due to its role in sensing amino acid deficiency 12 (Supplementary Fig

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[568] combined a hyperhydration strategy (1.2 g/kg glycerol + 26 mL/kg water) 2 h before commencing a two-hour cycling bout at 66% VO 2 max and 25 C with consuming (500 mL/hour) a sports drink and reported that glycerol hyperhydration failed to impact cardiovascular or thermoregulatory functions as well as endurance performance

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