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The tumor suppressor p53 limits ferroptosis by blocking DPP4 activity

These effects were amplified by selective erythropoiesis activation and inhibited by the ferroptosis inhibitor liproxstatin-1, indicating that Jak2VF signaling accelerates AS by promoting macrophage ferroptosis and erythrocyte phagocytosis (Liu W

These Bregs secrete cytokines including IL-10 to suppress the function of Th1 and Th17 cells, reduce the levels of inflammatory cytokines secreted by DCs, and promote the differentiation of Forkhead Box P3 (Foxp3 + ) Tregs (71, 72)